hrp0095p2-196 | Growth and Syndromes | ESPE2022

A retrospective analysis of short stature patients in the pediatric department of CHU Mustapha Pacha, Algeria between 2014 and 2022

Mustapha Noumi , Belbouab Reda , Boukari Rachida

Introduction: Growth retardation is a frequent reason for consultation in pediatrics. The interrogation, the reconstruction of the evolution curve of the height and the weight, the clinical and paraclinical examination make it possible to orient the diagnosis. The etiologies are multiple, but most often the growth retardation is isolated, it is then said to be constitutional.Patients and methods: This is a prospective de...

hrp0097p1-327 | Growth and Syndromes | ESPE2023

Growth results after GH treatment of children with juvenile idiopathic arthritis

Noumi Mustapha , Akretche Nora , Boukari Rachida

Introduction: Short stature is a very common complication of juvenile idiopathic arthritis (JIA). Chronic inflammation, long-term corticosteroid therapy, hepatic impairment and malnutrition can reduce the biological effects of IGF-1 and GH. Growth hormone (GH) treatment may improve height growth outcomes in patients with severe juvenile idiopathic arthritis (JIA). The aim of the study was to assess the response to growth hormone (GH) treatment in patients with...

hrp0095p1-132 | Growth and Syndromes | ESPE2022

The Study of Growth in Thalassemic Patients

Noumi Mustapha , Keddari Malika , Ferhani Yacine , Terrak Rachid , Boukari Rachida

Introduction: β-thalassemia is a chronic hereditary hemolytic anemia characterized by a defect in the synthesis of beta-globin chains, particularly common in the Mediterranean region, southern Asia, and the Middle East. Transfusion programs and chelation therapy have considerably extended the life expectancy of patients. This has led to an increase in the prevalence of complications related to iron overload, growth retardation is extremely common in polyt...

hrp0094p2-469 | Thyroid | ESPE2021

Thyroid dysfunction in Beta-thalassemia patients

Mustapha Noumi , Ladj MS , Rachid Terrak , Aissat L , Boukari R

Introduction: Β-thalassemia is a hereditary chronic hemolytic anemia characterized by a defect in the synthesis of beta-globin chains, particularly common in the Mediterranean region, southern Asia, and the Middle East Transfusion programs and chelation therapy have greatly extended the life expectancy of patients. This has led to an increase in the prevalence of endocrine complications, linked to iron overload The hypothyroidism is one of the most commonly reported comp...

hrp0097p2-235 | Diabetes and Insulin | ESPE2023

Frequency of autoimmune diseases in childhood type 1 diabetes

Noumi Mustapha , Khabtani Amina , Akretche Nora , Boukari Rachida

Introduction: Type 1 diabetes is frequently associated with other autoimmune diseases which can sometimes be integrated into autoimmune polyendocrinopathy. The objective of this study is to describe the frequency of autoimmune diseases in children with type 1 diabetes.Patients and Methods: A retrospective and descriptive study, involving 102 patients (54 males, 48 females) with type 1 diabetes followed in our department....

hrp0097p2-239 | Thyroid | ESPE2023

Hyperthyroidism in children

Noumi Mustapha , Allali Kawter , Khabtani Amina , Boukari Rachida

Introduction: Hyperthyroidism is a rare but potentially serious childhood disorder that, if left unchecked, can lead to a wide range of complications, including effects on growth and development. Medical history, physical examination and thyroid function tests help diagnose hyperthyroidism. Graves' disease is the most common cause of hyperthyroidism in children, accounting for over 95% of cases, and is caused by stimulating antibodies directed against the...

hrp0095p2-267 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Gonadal Dusfunction in Polytransfused Beta-Thalassemia Patients

Noumi Mustapha , Baghous Houssem , Keddari Malika , Belbouab Reda , Terrak Rachid , Boukari Rachida

Introduction: Β-thalassemia is a chronic hereditary hemolytic anemia characterized by a defect of synthesis of beta-globin chains, particularly common in the Mediterranean region, southern Asia, and the Middle East. Chelation therapy significantly prolonged the life expectancy of patients. This has led to an increase in the prevalence of endocrine complications, linked to iron overload. Gonadal Dusfunction is a frequent complication in polytransfused beta...

hrp0094p2-101 | Diabetes and insulin | ESPE2021

Disturbances of glucose homeostasis in polytransfused beta-thalassemia patients

Mustapha Noumi , N Khelafi , Y Ferhani , S Sokhal , R Terrak , R Boukari ,

Introduction: β-thalassemia is a hereditary chronic hemolytic anemia characterized by a defect in the synthesis of beta-globin chains, particularly common in the Mediterranean region, southern Asia, and the Middle East (1) Transfusion programs and chelating therapy have greatly extended the life expectancy of patients (2). This has led to an increase in the prevalence of endocrine complications, linked to iron overload (3) including abnormalities in gluco...